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Archive for the ‘embryology report’ Category

Here’s what my Embryos look like today compared to yesterday:

Embryo #:

Day Two Report

Day Three Report

1

2 cell, no fragmentation

4 cell, no fragmentation
2 2 cell, no fragmentation 4 cell, no fragmentation
3 2 cell, no fragmentation 4 cell, no fragmentation
4 2 cell, no fragmentation 3 cell, 15% fragmentation
5 4 cell, no fragmentation 4 cell, no change
6 4 cell, no fragmentation 4 cell, no change
7 4 cell, no fragmentation 4 cell, no change
8 4 cell, no fragmentation 6 cell, uneven growth – not looking great.

So … pretty good. We can probably say goodbye to #4 and #8. But that leaves us with 6 embryos with good potential. There’s some concern about #’s 5-7, but they still have time to continue growing. Embryos 1-3 had a slow start, but they clearly got the message that they should get a move on. I’ll get a call tomorrow with more news and a time for Saturday’s transfer.

And then on Saturday I’ll probably get a call moving my transfer to Sunday, just for kicks. 😉 I told that to my nurse while saying, “I hate to be such an optimist and all, but…” and she said, “Yeah, but you know, when you’ve been around the block a few times, you know how this works.” It’s all good. So far, the news is far better than IVF#1’s embryology reports were. Why, these are downright positive embryology reports!

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Things are looking up. My day 2 embryology report in IVF#1 was not promising at all. One of the reasons I was concerned that my fertilization report this cycle wasn’t as good as the fert. report with IVF#1 despite 40% more eggs retrieved was that I was concerned that I’d be facing the same fast attrition that I had faced with the subsequent embryology reports. But, so far, my fears appear to have been unfounded.

Today’s embryology report revealed that I have four 4-celled embryos and four 2-celled embryos. There is no fragmentation in any of them (unlike IVF#1).

So I’ve been moved to a Day 5 transfer.

Shabbos. Of course.

So I have to figure out the whole, you know, getting to the clinic on Shabbos thing. AGAIN. But other than that, I couldn’t be more thrilled.

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Day 6

No transfer today. Moving to a Day 6 transfer (tomorrow).

I, personally, think this is really all rather rude. I was waffling this morning about moving my afternoon meetings. If I moved them, for sure I was going to end up rescheduled, right? If I didn’t move them, I was going to end up with transfer staying on today’s schedule and having to cancel my meetings at the last minute. So, at 6:45, I rearranged my calendar, just in case.

And then, on my way in to work, my nurse called.

“Hi Perky One…”
“Oh this can’t be good.”
“We’re moving you to tomorrow.”
“Oh for the love of Pete.” (I admit I may have been, um, slightly less delicate than that)

Turns out, things are actually growing for a change (maybe we’ll even have something to freeze? Did I just say that?), but they’re growing slowly and unevenly and nothing’s made it to blast yet.

So… we’ll see what goes down tomorrow…

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I kinda left you all hanging about the embryology report didn’t I?

While I was at Ye Olde Fertility Clinic today, I ran into SuperDoc and he told me we are likely a go for tomorrow for transfer, but no promises. It will probably be a last minute call, but for the moment I’ll assume we’re a go for 1:15 tomorrow afternoon.

There’s at least one little embryo who could. Possibly another. Whether they’ll be blasts by tomorrow remains to be seen.

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Yes, people, I know it only takes one. I get that. But the cliche isn’t helping me right now. I have a right to wallow for a few hours in my less-than-stellar news, and that’s precisely what I’m going to do now, because today’s news was even less promising than yesterday’s news.

Let’s Review:

Going into Retrieval: We were expecting 4-6 eggs (not stellar news, but at least we were expecting not stellar news)

Retrieval Day: 10 eggs retrieved! (Double what we expected! A great number, all things considered)

Day 1 Fert. Report: Of the 10 eggs retrieved, 9 were mature (1 post mature) and all 9 fertilized and were 2 celled embryos (unbelievably good news! I was stunned and overjoyed by this news!)

Day 2 Embryology Report: 1 didn’t make it at all, 6 2-celled embryos still (1 with no change; not a good sign), 2 6-celled embryos (with 10-15% fragmentation, not good). Not a good enough report to warrant a 5 day transfer. Transfer scheduled for day 3 at 2pm. Disappointing news at best as with Single Embryo Transfers, they always try to go to blast in order to find the cream of the crop when possible.

Day 3 … (Today):

I’m on my way in to work and the weather is crappy, my head is pounding, my tushie is sore from the PIO shots, I’m cranky. You get it, right?

I’m walking out of my parking garage on my way into my office juggling my keys, my briefcase, a couple shopping bags (I bought candy to re-fill the candy jar I keep for people to snack on in my office), and my phone rings. I’m fumbling for it, but I have to pull off my glove (did I mention it’s snowing?) to get it open and turn it on; I almost miss the call. It’s my nurse at Ye Olde Fertility Clinic.

“Hi Perky One*, it’s NurseAwesome*. SuperDoc wants to talk to you.”
“Yeah? All right,” I sighed.
“You okay??”
“Yeah. Yeah, I’m fine.” I said, knowing that this just wasn’t going to bode well.
“Okay, hang on, here he is.”

Why the man couldn’t have just dialed the phone himself is beyond me. Because that introduction is exactly what gave me the anxiety I had, you know. But whatever. I do love him, and I know he has my best interests at heart. And for all I know it was NurseAwesome that wanted to make the call to me so that she could guage how I was doing, since she knows how pissy I’ve been all cycle. (Update: It turns out that SuperDoc did call me directly himself – but he called me at home and left a message at 8:45. Of course, I wasn’t home – I was on my way to work. NurseAmazing knows better, and she knows me well enough to know that I probably wouldn’t have been okay with just hearing a voicemail on my home number … which I may or may not have checked before I went in for my appointment this afternoon, by the way … so she probably said, “Yeah, no, we’re going to call her cell phone now.” That’s why I love her.)

So he said he took a look at the embryos with the embryologist this morning and what I’ve got is a 7-cell, a 6-cell, a 5-cell, and 2 four cells. If I were any other patient, with their normal criteria, he’d be recommending a two-embryo transfer today (day 3), but he does NOT recommend that with my history. With HOMs at home, and with my pregnancy history (e.g. not good) and with my need to ensure I do not get pregnant with twins (unless, you know, they’re monozygotic, in which case, we just had no way of controlling that risk), he is wholly opposed to a 2-embryo transfer. Which is good, because I am also opposed to it. My exact words were “absolutely not.” And he responded, “We are on the exact same page, don’t worry, I’m not recommending it – I would caution against it.”

My embryos look pretty crappy. They do not meet the criteria to go to a 5 day blast, but given the choice between picking a crappy single embryo for transfer today as planned or trying to grow one to blast by Thursday or Friday, he thinks our chances are better if we wait. He believes we are likely to have one at the blast stage if we wait.

So what happens if we don’t have any blasts by Thurs/Fri? We transfer whatever the best we’ve got is. And what if there’s nothing? We scrap the whole thing and start over. After all, we were all set to cancel this cycle last week before we got to retrieval, remember? It’s really no different, except that now we’ve been through a lot more hell than if we’d canceled ahead of time. But at least now we’ve got more information, right? What I don’t know is whether this would count as a full IVF cycle for insurance purposes if we don’t make it to transfer. My guess? Once you get to retrieval, it counts. That being said, my doctor is confident that we’ll have something to transfer either Thursday afternoon or Friday morning, it’s just a question of quality.

And so it goes.

*Note, she did actually use our real names… she doesn’t refer to herself as “NurseAwesome” though she’d be perfectly justified in doing so.

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Today’s news isn’t as great as yesterday’s news.

To review, yesterday we had 9 two-celled embryos from our nine mature eggs retrieved, which was fantastic news. I was overjoyed, shocked, and amazed.

Today:

1 didn’t make it at all.
6 are still 2 celled embryos (1 has had no change and therefore will not make it to tomorrow)
2 are 6 celled embryos, but they are breaking down (fragmented) and are unlikely to make it.

Transfer tomorrow at 2pm, unless I hear otherwise. Not looking great for having anything to freeze by Thursday (they bring everything to blast for freezing at my clinic, as they find they have a much higher FET success rate that way).

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